On April 23, 2021, an online meeting of the Central Asian Foreign Ministers and the US Secretary of State took place in the C5 + 1 format. The Minister of Foreign Affairs of the Republic of Tajikistan Sirojiddin Muhriddin participated in the meeting and made a speech.
During the meeting, the parties discussed the issues related to the current state and prospects of cooperation in the region, countering international terrorism and extremism, combating COVID-19 and the consequences of climate change.